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PhD position - Surface enhanced spectroscopy to study electrochemical reactions in a microfluidic chip
Published(1090 days ago)
Deadline for applications(1067 days ago)
University of Twente (UT)Enschede (Niederlande)
PhD position: Surface enhanced spectroscopy to study electrochemical reactions in a microfluidic chip
Location Enschede Function types PhD positions Scientific fields Engineering Hours 38.0 hours per week Salary € 2191 - € 2801 Education University Graduate Job number 884006 About employer University of Twente (UT)
Electrochemistry is a well-studied method for the mimicry of drug metabolism that is complementary to other in vitro
techniques like liver microsomal incubations. Additionally, exciting developments have been reported in recent years
with respect to protein analysis comprising the electrochemical reduction of disulfide bonds, important for biopharmaceutical
protein analysis, and the specific cleavage of peptide bonds, relevant for proteomics.
In this project, the aim is to develop microfluidic chips for in-situ analysis to gain a better understanding of the reactions
occurring at the electrode-solution interface. This microfluidic chip will contain ordered nanofabricated structures for surface
enhanced Raman spectroscopy (SERS), or structures for surface enhanced infrared absorption spectroscopy (SEIRAS). SEIRAS and
SERS are two complementary methods, since vibrations active in SERS are inactive in SEIRAS and vice versa. Moreover, enhancement
of the spectroscopic methods is essential to lower the limit of detection.
For questions regarding this position contact Mathieu Odijk (firstname.lastname@example.org). Please submit your application using
the on-line form at www.utwente.nl/vacatures , including a C.V. and motivation letter. The deadline for submission is
February 15th 2017. Please do NOT send your C.V. and motivation letter by email. Postdoctoral research do not need
to apply, as we are specifically looking for a prospective PhD student.
We are looking for a candidate with a Master’s Degree in a relevant field, like e.g. electrical engineering, nanotechnology,
(analytical) chemistry, chemical engineering, or physics. The candidate should be able to work independently, and have excellent
theoretical and experimental skills. Fluent command of English is required. Knowledge or experience in micro- and nanofabrication
is considered as a key advantage. Moreover, knowledge in microfluidics, optics/waveguides and spectroscopic methods such as (surface
enhanced) Raman and/or Fourier transform infrared spectroscopy is also greatly appreciated.
Most importantly, the BIOS Lab-on-a-Chip group in general, and this project in particular are very challenging multidisciplinary
environments. It is therefore essential to show willingness to look beyond disciplinary boundaries, to learn new techniques and
skills required for this project.
Conditions of employment
PhD students are employed for a period of 4 years. Salary and conditions are in accordance with the Collective Labor Agreement
(CAO) of the Dutch Universities. The gross monthly salary starts at € 2191,- gross per month in the first year, leading up to
€ 2801,- gross per month in the last year excluding allowances in accordance with the job profile ’Promovendus’, under the University System for Job Classification (UJC).
Employees are also entitled to a holiday allowance of 8% of the gross annual salary and a year-end bonus of 8.3 %.
The University of Twente. We stand for life sciences and technology. High tech and human touch. Education and
research that matter. New technology which drives change, innovation and progress in society. The University of Twente is the
only campus university in the Netherlands; divided over five faculties we provide more than fifty educational programmes. The
University of Twente has a strong focus on personal development and talented researchers are given scope for carrying out pioneering
The faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS) comprises three disciplines that
shape Information and Communication Technology. ICT is more than communication. In almost every product we use mathematics, electronics
and computer technology and ICT now contributes to all of societies activities. The faculty works together intensively with industrial
partners and researchers in the Netherlands and abroad and conducts extensive research for external commissioning parties and funders.
The research which enjoys a high profile both at home and internationally, has been accommodated in the multidisciplinary research
institutes MESA+, CTIT and MIRA.
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