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Doctoral candidate (Ph.D student) Department of Cardiology and Pneumology (f/m)
Published(1081 days ago)
Deadline for applications(1056 days ago)
University Medical Center GöttingenGöttingen
Within the cardiovascular SFB1002 "Modulatory Units of Heart in Heart
Failure" especially the Department of Cardiology and Pneumology is
Doctoral candidate (Ph.D student)
limited for three years
part-time position, 65 % | salary according to TV-L
The University Medical Center Göttingen is a tertiary care center and
offers great development potential. Its 7,400 employees work in over 65
departments and facilities to provide top-quality patient care, excellent
research and modern teaching. Göttingen, "City of Science", lies near
the center of Germany, the University Medical Center Göttingen is
embedded in the city’s attractive network of scientific research
Cardiac research is a dedicated research focus of the University
Medical Center Göttingen. Several departments are collaborating in the
Heart Research Center Göttingen (HRCG) with its Collaboratice
Research Center "SFB1002" and its International Graduate Programme
on Cardiovascular Sciences (including DFG IRTG 1816). The HRCG is
also a member of the German Center for Cardiovascular Research
Our research group on "Cardiac remodeling" belongs to the Division of
Cardiology and Pneumology (Director: Prof. Dr. G. Hasenfuß) and is
funded by the SFB1002 (TP D04):
The group consists of: PD Dr. K. Toischer, Prof. A. Fischer, Dr. B.
Mohamed, D. Lbik, MD students and technicians.
The goal of this project is to study the effect of different epigenetic
mechansims on the development of heart failure. The focus of this
project is the role of RNA-Methylation. Preliminary data suggest distinct
role in cardiac hypertrophy vs. heart failure. A new mouse model to
influence RNA methylation is available. Also cell culture experiments
and the description in human tissue is part of this project.
The following technics shall be performed by the applicant:
Operation of mice (transversal aortic constriction)
Molecular and histological analyses
In-vitro and in-vivo experiments with AAV
iPS-derived cardiomyoycytes cell culture
Next generation sequencing and epigenetic analyses
Trained and highly motivated student (Master of science or equal)
having experience in basic science, molecular biology, cell biology,
physiology or similar disciplines. Knowledge and practical skills in
handling of mice and interventions are desirable.
Women are especially encouraged to apply. Applicants with disabilities
and equal qualifications will be given preferential treatment.
We look forward to receiving your application by October 31th, 2016.
University Medical Center Göttingen
Department of Cardiology and Pneumology
PD Dr. Karl Toischer
Tel.: 0551/39-66380, Fax: 0551/39-66380
Web: http://herzzentrum-goettingen.de/en/content/ research/1510.html
Travel and application fees cannot be refunded or
Please send your application only via e-mail as a