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University Medical Center Göttingen
Universitätsmedizin Göttingen
Within the cardiovascular SFB1002 "Modulatory Units of Heart in Heart Failure" especially the Department of Cardiology and Pneumology is seeking a
Doctoral candidate
(Ph.D student)
limited for three years
part-time position, 65 % | salary according to TV-L
The University Medical Center Göttingen is a tertiary care center and offers great development potential. Its 7,400 employees work in over 65 departments and facilities to provide top-quality patient care, excellent research and modern teaching. Göttingen, "City of Science", lies near the center of Germany, the University Medical Center Göttingen is embedded in the city’s attractive network of scientific research facilities.
About us:
Cardiac research is a dedicated research focus of the University Medical Center Göttingen. Several departments are collaborating in the Heart Research Center Göttingen (HRCG) with its Collaboratice Research Center "SFB1002" and its International Graduate Programme on Cardiovascular Sciences (including DFG IRTG 1816). The HRCG is also a member of the German Center for Cardiovascular Research (DZHK).
Our research group on "Cardiac remodeling" belongs to the Division of Cardiology and Pneumology (Director: Prof. Dr. G. Hasenfuß) and is funded by the SFB1002 (TP D04):
The group consists of: PD Dr. K. Toischer, Prof. A. Fischer, Dr. B. Mohamed, D. Lbik, MD students and technicians.
The project:
The goal of this project is to study the effect of different epigenetic mechansims on the development of heart failure. The focus of this project is the role of RNA-Methylation. Preliminary data suggest distinct role in cardiac hypertrophy vs. heart failure. A new mouse model to influence RNA methylation is available. Also cell culture experiments and the description in human tissue is part of this project.
The following technics shall be performed by the applicant:
  • Operation of mice (transversal aortic constriction)
  • Echocardiography
  • Molecular and histological analyses
  • In-vitro and in-vivo experiments with AAV
  • iPS-derived cardiomyoycytes cell culture
  • Next generation sequencing and epigenetic analyses
  • Bioinformatical analyses
Your profil:
Trained and highly motivated student (Master of science or equal) having experience in basic science, molecular biology, cell biology, physiology or similar disciplines. Knowledge and practical skills in handling of mice and interventions are desirable.
Women are especially encouraged to apply. Applicants with disabilities and equal qualifications will be given preferential treatment.
We look forward to receiving your application by
October 31th, 2016.
University Medical Center Göttingen
Department of Cardiology and Pneumology
PD Dr. Karl Toischer

37099 Göttingen
Tel.: 0551/39-66380, Fax: 0551/39-66380
E-Mail: ktoischer@med.uni-goettingen.de
Web: http://herzzentrum-goettingen.de/en/content/
Travel and application fees cannot be refunded or
Please send your application only via e-mail as a
PDF-file. Logo

Closing date: 31.10.2016
Closing date: 31 October 2016 Published on academics.com on date 6 October 2016
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