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Proteomics in Time and Space

'Proteomics' is the large-scale study of proteins, particularly their structures and functions. The large EU project PROSPECTS is a collaborative research effort of leading European scientists in the Proteomics field. PROSPECTS now presents a number of breakthroughs in a series of articles comprising a "Special Issue" of the top journal of the field: Molecular & Cellular Proteomics. Coordinated by Matthias Mann, director at the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, the scientists lay out their contribution to the future of proteomics with a powerful and versatile set of assay systems for characterizing proteome dynamics.

"Proteomics specification in time and space" (PROSPECTS) is a five year collaborative project that commenced early in 2008 and is funded by the Research Directorate of the European Commission under the 7th Research Framework Program. PROSPECTS brings together ten leading research groups from around Europe, as well as Thermo Fisher Scientific, a mass spectrometry instrument manufacturer and chromatography company. The different groups seek new insights into the cellular function of proteins and their aberration during diseases. "We here present a perspective on how the proteomics field is moving beyond simply identifying proteins," says Matthias Mann. "It now provides powerful tools for characterizing proteome dynamics and thereby creates a new level of proteomics research." The "Special Issue" contains a series of 16 original research papers documenting the recent progress in all aspects of proteomic research achieved within PROSPECTS.

Original publications Mann et al.: Proteomics in Time and Space. MCP, March 7, 2012 <www.mcponline.org/site/home/special_issues/>

Contact Prof. Dr. Matthias Mann Proteomics and Signal Transduction Max Planck Institute of Biochemistry Am Klopferspitz 18 82152 Martinsried E-Mail: mmann@biochem.mpg.de <www.biochem.mpg.de/mann>

Dr. Anne Katrin Werenskiold Project Manager Max Planck Institute of Biochemistry Am Klopferspitz 18 82152 Martinsried Phone: +49-89-8578 2601 E-Mail: kwerensk@biochem.mpg.de <www.biochem.mpg.de/facilities/eu/index.html>

idw :: 07.03.2012