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Postdoc in Computational Structural Biology (f/m)
Published(292 days ago)
Deadline for applications(270 days ago)
Forschungszentrum Jülich GmbHJülich
As a member of the Helmholtz Association, Forschungszentrum Jülich makes an effective contribution to solving major challenges facing society in the fields of information, energy, and bioeconomy. It focuses on varied tasks in the area of research management and utilizes large, often unique, scientific infrastructure. Come and work with around 5,900 colleagues across a range of topics and disciplines at one of Europe‘s largest research centres.
The Computational Structural Biology Group at the Institute of Complex Systems 6 (ICS-6) works broadly on methods interpret cryo-electron microscopy (cryo-EM) data. The group develops computational tools to build atomic models of biomelecules with data from cryo-EM experiments. We also develop new methods for the processing of single-particle cryo-EM Images with a focus on the Analysis of protein dynamics. We apply these techniques in particular on the structure Determination of amyloid fibrils that are involved in neurodegenerative diseases.
We are looking to recruit as soon as possible a
Postdoc in Computational Structural Biology
Further development of our real-space refinement program DireX, including efficient parallelization
Using similar tools to also perform novel volume (3D density map) modification approaches, which require highly efficient algorithms
Further development of our new de novo protein modeling approach EMfasa
Contribute to the development of new approaches to analyze protein dynamics from cryo-EM data
Apply the new methods to projects on amyloid structures within the group and to other projects with external collaborators
PhD in Physics, Chemistry, Biology, Biochemistry, Bioinformatics, Computer Science or comparable
Experience in structural biology and/or modeling and refinement of protein structures and/or molecular dynamics simulations and/or Image processing and 3D reconstructions
Programming experience with C/C++ and Python
Method development and application of cryo-EM, which enables strong interaction between theory and Experiment
A wide range of scientific challenges
Excellent research infrastructure
International, interdisciplinary working environment on an attractive research campus, ideally situated between the cities of Cologne, Düsseldorf, and Aachen
A comprehensive further training programme, including English language courses
Flexible working hours and various opportunities to reconcile work and family life
Limited for 2 years with possible longer-term prospects
Full-time position with the option of slightly reduced working hours
Salary and social benefits in conformity with the provisions of the Collective Agreement for the Civil Service (TVöD)
Forschungszentrum Jülich aims to employ more women in this area and therefore particularly welcomes applications from women.
We also welcome applications from disabled persons.
We look forward to receiving your application, preferably via our online recruitment system on our career site until 16.03.2018, quoting the reference number 2018-052.
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