The Max Planck Institute for Biophysical Chemistry is one of the largest institutes of the Max Planck Society for the Advancement of Science and conducts basic research to advance knowledge and benefit society. Innovative projects and interdisciplinary cooperation characterize research within the Max Planck Society.
The research group of Quantitative and Systems Biology (Juliane Liepe) invites applications for a position as
– Mechanistic Modelling in Computational Immunology –
(Code number 02-21)
The aim of this project is to develop the mechanistic model components of the antigen processing and presentation (APP) pathway and to integrate those into a comprehensive APP mechanistic model. This project is a cornerstone of a bigger project of Juliane Liepe, “Integrative mechanistic and multi-omics Modelling of Antigen Presentation to predict epitope dynamics – IMAP”, recently funded by the prestigious ERC Starting grant (ERC-StG) fund. The IMAP project will start on April 1st, 2021 and will finish on March 31st, 2026.
Liepe lab is a dynamic environment where computational biology leads, through international collaborations, a broad range of leading researchers in biology, molecular and structural biology, genomics and immunology, with the final goal of developing tools and knowledge with translational applications in cancer, infection and autoimmunity, such as: Liepe et al., Science 2016 and Blankenstein et al., patent PCT/EP2019/050027.
The candidate will work closely with experimentalists and analyse experimental data, ranging from in vitro to in vivo experiments, with the aim to develop models of the APP pathway. To do so, the candidate will develop and employ new data analysis and modelling approaches.
PhD or equivalent degree in either Computational Biology, Computing, Mathematics, Bio-Engineering or Physics
strong background in mechanistic modelling of biological systems, experience with Bayesian parameter inference
strong background in scientific programming, working in Linux server environment
interest in signalling pathway, immune system, T cells, mass spectrometry, proteomics
The appointment is for two years and may start immediately. The payment and benefits are based on the TVöD guidelines.
The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.
Please send your application including a short letter of motivation, CV, a list of publications, and email addresses of two referees preferably via email as single PDF file with reference to the code number to email@example.com.
Max Planck Institute for Biophysical Chemistry
Research Group Quantitative and Systems Biology
Am Fassberg 11