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German Center for Neurodegenerative Diseases (DZNE)Bonn
The German Center for Neurodegenerative Diseases (DZNE) is a unique
non-university research center which is dedicated to the subject dementia
and all its areas, as well as other neurodegenerative diseases. The center
compasses the full spectrum of fundamental research through population
sciences to health care research. The DZNE stands for excellence in research
and science management, translation of scientific results into practice, interdisciplinarity
and internationalization. It is a research center within the Helmholtz
Organization of German research centers. With over 1,000 employees from
55 nations, spread over 10 sites, the DZNE is one of the national and international
leading research centers in its research field.
Population Health Sciences is one of the major scientific areas of the DZNE
in Bonn, Germany. We aim to understand the complex and heterogeneous
causes of neurodegenerative and other age-related diseases in order to
contribute to their effective, individualized prevention and treatment. Specifically,
we investigate the interplay between the genome and the exposome in
determining health status. Our research is based on the Rhineland Study, a
population-based cohort that will include more than 20,000 people aged 30
years and over and is designed to run for decades.
The DZNE in
The Rhineland Study emphasizes deep phenotyping. Besides detailed clinical
data we collect extensive 'omics' information from all our participants, including
genomic, epigenomic, transcriptomic, metabolomic, proteomic as well as
microbiomic data. These multi-omics data are of critical importance to most
of our ongoing as well as future research projects which aim to identify and
understand the molecular and biochemical pathways that mediate the effects
of various risk factors on brain structure and function.
You will be responsible for the management and further development of
the multi-omics platform of the Rhineland Study. You will be supported by a
bioinformatician and a team of young scientists working on various aspects
of the omic analyses. You will play a key role in many of the groups' research
projects. In addition, you will have the opportunity to develop and lead your
own research line as it fit within the general research interests of our group.
Processing and analyzing our multi-scale omics data (including genotyping
arrays, DNA/RNA sequencing and metabolomics data)
Supervision of graduate students
Analysis of data and preparation of manuscripts for publication in peerreviewed
Maintaining contacts and active collaborations with internal and external
academic and industrial partners
Preparation of grant applications
We are looking for a highly talented, motivated, enthusiastic and ambitious
researcher with good social skills. Successful candidates have a PhD in
computational biology, genomic epidemiology, biostatistics, (bio)medical
sciences or a related discipline and extensive experience in bioinformatics
and large-scale multi-omics projects, including genomics, epigenomics, transcriptomics
or metabolomics. Demonstrated interest in quantitative research,
strong analytical skills, ability for independent and critical thinking, leadership
capabilities and excellent communication and writing skills in the English
language are a prerequisite.
Interesting and challenging work on the forefront of health research
Working in a highly interdisciplinary and international team
A high potential for the development of own research profile
The position is initially for 2 years, extension possible
Job location is Bonn, Germany. Common language at work is English
Employment, payment and social benefits are determined by the Public
Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst -
The professional qualification of early career researchers is of great importance
for DZNE. Besides special offers for career development and support, the DZNE
also provides researchers career opportunities in form of junior research groups
or internal career paths to obtain scientific independence.
You will obtain special skills and knowledge for your scientific qualification
during your activities at DZNE. The DZNE is an equal opportunity employer.
It is committed to employing disabled individuals and especially encourages
them to apply.
Please apply via:
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