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Doctoral candidate (f/m/d) NutriAct
Published(358 days ago)
Deadline for applications(334 days ago)
Leibniz-Institute for Vegetable and Ornamental CropsGroßbeeren
The Leibniz-Institute of Vegetable and Ornamental Crops (IGZ) conducts research in horticulture and related sciences, to promote a sustainable production of vegetables. We are a plant science institute, with a view on the use of plants as food and in our living environment.
Our institute is interested in the generation of highly nutritional plant-based food. The work contributes to a sustainable production of high quality horticultural products meeting the consumer demands.
Within the BMBF joint project "Nutritional Intervention for Healthy Aging: Food Patterns, Behavior and Products" (NutriAct) the Department of Plant quality and food security of the IGZ in cooperation with the Junior Research Group ProAID located at the Institute of Nutritional Science at the University of Potsdam is looking for a
Doctoral candidate (f,m,d) NutriAct
Employment will be available for 36 months and the salary will be according to wage group EG 13 (TV-L, salary domain east, 65 % of the regular working time) depending on candidate skills and experiences. Places of work will be at the Leibniz-Institute of Vegetable and Ornamental Crops in Großbeeren and the location of the Junior Research Group ProAID in Bergholz-Rehbrücke. There is the opportunity for doctoral studies at the Faculty of Mathematics and Natural Sciences of the University of Potsdam under the supervision of Prof. Susanne Baldermann.
A plethora of secondary plant metabolites are known to affect the cellular metabolism in vivo and reveal beneficial effects on human health. However, the underlying processes are just marginally understood, but interactions of secondary plant metabolites with endogenous proteins are assumed as potent mechanistic link that modify cellular metabolism based on the introduction of posttranslational modifications resulting in the modulation of protein function. Hence, the aim of the present project is to identify and characterize adducts of endogenous proteins and secondary plant metabolites and additionally evaluate their effects on the metabolism in detail. In this context, the studies are based on cell culture experiments as well as optionally animal studies and human studies.
analyses of selected plant metabolites in particular metabolites from the protein and secondary metabolism
studies of selected issues on bioavailability and metabolism of selected secondary and primary plant metabolites
identification and characterization of posttranslational protein modifications and their effects on cellular metabolism
conception and evaluation of experimental settings (in vitro and in vivo)
publishing of research results
Skills and requirements:
a highly motivated candidate with a master or equivalent degree in food chemistry, nutritional science, biology, bio-chemistry, or related disciplines
effective knowledge in modern analytical techniques like HPLC/MS and GC/MS
basic knowledge in molecular biological methods and protein analytics are favorable
contribution to animal experiments and human intervention studies
excellent English communication skills
an ability to work independently in an interdisciplinary research field
driver license valid in Germany and corresponding to German Class B
a research project where you will have the possibility to interact with many researchers working on a broad range of topics
an attractive workplace in an excellently equipped laboratory in the Berlin area
option for advanced training e.g. provided by the Potsdam Graduate School (PoGS)
Contact: Prof. Susanne Baldermann (033701 78 241; firstname.lastname@example.org) or Dr. Andrea Henze (033200 88 5225,
email@example.com). Further information can also be found in recent publications from our lab: e.g.
Schröter et al. Food Chem. DOI: https://doi.org/10.1016/j.foodchem.2017.11.043; Frede et al. JAFC, DOI: 10.1021/acs.jafc.7b01929, Henze et al., Sci Rep |
doi: 10.1038/srep37346; Henze et al., J Cell Mol Med | doi: 10.1111/jcmm.12446.
The IGZ is an equal opportunity employer. Handicapped people with equal qualifications will be employed preferentially. The IGZ wishes our staff to reflect the diversity of society and thus
welcomes applications from all qualified candidates regardless of age, gender, race, religion or ethnic background.
Please send your application citing the reference number by 06/2019/3 of 18.02.2019 to: Personalbüro, Institute for Vegetable and Ornamental Crops, Theodor-Echtermeyer-Weg 1,
D-14979 Großbeeren or online in pdf-format to firstname.lastname@example.org.
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